General inquiry and information about detecting heart attacks

General inquiry and information about detecting heart attacks

Introduction

Misdiagnosis of heart attacks has been reported in about one third of patients. Statistics from studies in a few areas have revealed that about one third of patients had a diagnosis that was different from that of the first diagnosis. This makes it necessary to be aware how to report symptoms during an emergency or when seeking general inquiry and information. Here are top tips that can help you understand how to detect a heart attack and also when to seek clarifications when in doubt.

Which is the best test to detect heart attack?

There are various tests that are used to detect a heart attack. It is wrong to assume that there is a best test to detect heart attack. A combination of tests are usually performed to come up with a complete diagnosis. All of the tests that are typically performed have their own advantages, and the choice of tests depends on various factors. The symptoms reported by the patient, the condition of the patient and the initial assessment at the hospital will determine the sequence of tests. Therefore, what you report at general inquiry and information you provide about medical history will have a bearing on the tests.

What are the common or primary tests performed to detect a heart attack?

The following tests are considered as the primary tests to detect a heart attack. As mentioned above, the choice of these tests will depend on the condition of the patient, the symptoms and medical history.

1.Electrocardiogram – Abbreviated as ECG or EKG, this test is to measure the electrical activity of the heart. The test is performed by attaching electrodes on the chest, arms, and legs which are then connected to a machine. The test captures the timing and the strength of electrical signals in the heart. During this test, electricity is not passed through the body, but the signals are monitored. The ECG detects abnormal heart rhythms, possible heart muscle damage, and heart attacks that have occurred in the past.

2.Blood tests – These tests are conducted to confirm a heart attack by reading markers in the blood that indicate damage to heart muscle.  During heart muscle damage or injury, a specific protein, and a specific enzyme are released in the blood. The blood test detects the presence of this protein and enzyme to indicate if you have had a heart attack. When you make a general inquiry and information request about tests for heart attack, most hospitals give a quick explanation about these tests.

The different markers, such as protein/enzyme that are released during a heart attack include the following:

  • Troponin – this is a protein that has typically very low levels in the blood in a person. During a heart attack when the muscle is damaged, this protein is released and results in elevated levels. Tests that indicate higher levels of Troponin offer confirmation of a heart attack.
  • Creatine Kinase-MB (CK-MB) – this is another enzyme that helps understand muscle damage during a heart attack. The levels of this enzyme increase in the blood following damage to heart muscle, and blood tests with elevated levels confirm a heart attack.
  • Myoglobin – this is also considered as an early indicator of heart muscle injury. However, it is not as specific as the protein troponin, and is therefore not the preferred test.

3.Chest X-ray – This imaging test is often carried out after the ECG and blood tests, and is not always the first test in a hospital. The purpose of the test is to capture an image of the heart, lungs, and blood vessels. This will help detect the size of the heart size, and build-up of fluid in the lungs. Additionally, this also captures other conditions and helps in understanding the reason behind reported symptoms during general inquiry and information.

4.Echocardiogram – this is another test that follows the usual initial tests. This involves the use of ultrasound waves to record a moving image of the heart. This helps to understand the functioning of the heart, and the movement of the heart’s walls. This also captures damage to the heart muscle.

The test involves the use of a transducer, that sends sound waves to the heart. The echoes of sound waves are captured as images for an interpretation of various parameters.

5.Other tests – In addition to the above, other tests include coronary angiography, cardiac MRI, CT coronary angiography and stress tests. These tests are more advanced in nature and are usually performed after the initial tests are conducted.

How to detect heart attack and common symptoms?

Looking for general inquiry and information about common symptoms of a heart attack? The following is a short list of typical and common heart attack symptoms:

  • Chest pain with a sensation of tightness and pressure due to a squeezing feeling, apart from pain.
  • Abnormal pain and discomfort that radiates across the upper body. For example, the shoulder, arms, back, neck, jaw.
  • Breaking out in to a cold sweat.
  • Sudden overall tiredness.
  • Unusual heartburn or a feeling of indigestion.
  • A lightheaded feeling or feeling dizzy.
  • Possible nausea.
  • Difficulty breathing.

Women are known to have certain uncommon symptoms like a sudden feeling of sharp pain in the neck, the arms or the back.

What you can do if you see someone with signs of a heart attack?

In the event of witnessing a person with possible signs of a heart attack, the following actions may be performed.

  • Call for emergency medical assistance.
  • If the person has stopped breathing or if a pulse cannot be felt, you can begin cardiopulmonary resuscitation (CPR), if trained.
  • If the person is known to you and had been recommended nitroglycerin or aspirin for emergencies, give the respective medicine.
  • Wait for emergency health care professionals to arrive.

How will genetic testing help?

Genetic tests help to detect risk of heart attack linked to genetic makeup of individuals. These tests analyze DNA of a person to identify genetic variants that are known to contribute to cardiovascular diseases. Certain inherited risk factors are not detected through traditional risk diagnosis.

Genetic tests involve collection of saliva or blood sample for DNA analysis. This looks for specific genetic markers or variants linked to heart disease. This is compared with known risk profiles to understand the person genetic predisposition to risk of heart disease. This information is always viewed or taken in combination with other analysis or diagnosis to offer you a comprehensive risk assessment.

The main benefits of genetic testing are early detection and pre-emptive treatment to prevent risk of heart attack. These tests are now available in Tamilnadu and can help you understand genetic risk to self and family members who have similar genetic profiles.

Medically Reviewed by

Dr.Rajasekar Cardiologist

Dr. Rajasekar is a cardiologist in Chennai, with extensive experience in the field. He completed his MBBS from Madurai Kamaraj University, followed by an MD in General Medicine and a DM in Cardiology from The Tamil Nadu Dr. M.G.R. Medical University (TNMGRMU).

What Are The Ideal Diagnosis For Confirmation Of Heart Attack?

What Are The Ideal Diagnosis For Confirmation Of Heart Attack?

Introduction

Failure to detect certain types of heart ailments and conditions are responsible for high fatalities. A recent study by the American Heart Association showed that one third of people with Type 2 heart attacks were not diagnosed or receiving treatment. As a result of this, patients ended up with delayed confirmation of heart attack with a clear increase in death rates. Here are top reasons why you need to know more about the right diagnosis of heart attack, and conditions that are commonly confused with heart attacks.

Does ECG detect heart attack?

Yes, ECG/EKG is the most common initial test that you may undergo if you report symptoms of a heart attack. Based on the ECG results, you may then have to undergo other tests for confirmation of heart attack. Here’s a little fact to clear a possible confusion. ECG and EKG are the same, both are different abbreviations and spellings of the same test electrocardiogram. In German language, this test is spelt with a ‘k’, as electrocardiogram, and thereby has a different abbreviation of EKG.

How long does it take for an ECG test?

Typically, it takes between 5 to 10 minutes for an ECG test. Interestingly, an ECG can actually detect a heart attack that a person may have had in the past, if there is dead heart muscle. This could actually show if you have had a heart attack many years ago, if there is dead heart muscle.

What to expect during an ECG test?

As outlined above, this is a simple test, to evaluate the heart and give confirmation of heart attack. This involves placing small electrodes at specific spots on your chest, arms, and legs. These electrodes are then connected to the ECG machine. The electrodes convey electrical activity of the heart, which is measured and the results are interpreted from the prints. In case you are apprehensive of electric currents, be assured that during the test, electricity is not sent to the body in any way. The leads that connect the electrodes to the ECG machine only convey the electrical signals to the machine and do not sent electricity to the body.

The ECG records shows how fast your heart is beating and the rhythm of your heart beats. For instance, if the heart beats are steady or irregular. Any changes recorded during the test may indicate heart conditions that require further testing or treatment.

What do the results of an ECG indicate?

The results of an ECG help doctors with data for confirmation of heart attack. For instance, the following is determined:

  • Identifying the cause of chest pain reported by you.
  • Assessing problems such as severe tiredness, difficulty breathing, feelings of dizziness and fainting.
  • Identifying irregular heartbeats.
  • Assess overall heart health for treatment for a heart attack. 
  • To record a baseline of the heart’s function, for comparison with future ECGs.

The danger of underlying heart conditions remaining undetected

There is a clear danger when underlying heart conditions are not detected on time. A recent study shows that more than two thirds of people who have had a heart attack due to reasons other than blood clots, have some undetected heart condition. While tests can help with confirmation of heart attack, after the actual attack, it is always best to know about underlying conditions before the attack. This will help in preventing fatalities and also help to reduce the risk of attacks.

The American Heart Association reported findings about people who had Type 2 heart attacks, caused by strains due to infections or high rate of heart beats. This has the effect of reducing blood pressure levels or oxygen levels in the blood. During the study, advanced heart imaging tests were conducted and it was revealed that patients had narrowed arteries or weakened heart muscles. These were in most cases not diagnosed, and a very small number of patients had received treatment. 

This makes it necessary to undergo other tests to determine the underlying conditions in time. Genetic testing holds out great promise as it helps detect the genetic component of certain underlying conditions. In other words, you can determine if you are genetically predisposed to certain conditions. Armed with this information, you can seek timely treatment and make suitable changes in lifestyle to reduce the risk of heart attacks.

What is the difference between type 1 and type 2 heart attacks?

Heart attacks that are commonly known are known as Type 1 myocardial infarction. This refers to the condition wherein blood supply to the heart is affected. This is typically due to a blood clot, that results in the death of a particular area of heart muscle.  

Type 2 myocardial infarction refers to the condition when there is damage to the heart muscle due to strain from certain conditions. Here, blood supply is affected, reducing oxygen levels, and this puts a strain on the heart, ultimately resulting in damage to the muscle.

Troponin tests, type 2 heart attacks and undiagnosed conditions

Tests that help with confirmation of heart attack include the Troponin tests. These are highly sensitive blood tests that check for troponin levels in the blood. This protein is released into your blood when your heart muscle undergoes some kind of damage. This lets the specialist quickly diagnose if you have had a heart attack.

Interestingly, about 50% of patients with high troponin levels are recorded as having had Type 2 heart attacks. However, less than 33% of these patients had not been diagnosed or had not received treatment. Due to the failure to detect and treat the conditions, fatalities increased.

How genetic testing can help detect underlying conditions to prevent heart attacks?

Simple genetic testing can uncover if you are genetically predisposed to certain underlying conditions. The reasons for heart attacks are broadly classified into the following:

  1. Genetics
  2. Lifestyle
  3. Existing medical conditions
  4. Environment
  5. Age, gender
  6. Medications
  7. Depression, anxiety

Out of these reasons, it is possible for a person to be aware of most of the causes, through a simple session with a cardiologist. For example, you can learn of how environment, medicines, depression, anxiety, lifestyle, and existing medical conditions affect your chances of a heart attack. However, the genetic component of risk, can only be determined by tests. Simple blood or saliva samples can help uncover your risk of a heart attack. Advanced facilities are now available in Tamilnadu, that can help clear your apprehensions, or help you make suitable modifications in lifestyle to reduce your risk.

Medically Reviewed by

Dr.Rajasekar Cardiologist

Dr. Rajasekar is a cardiologist in Chennai, with extensive experience in the field. He completed his MBBS from Madurai Kamaraj University, followed by an MD in General Medicine and a DM in Cardiology from The Tamil Nadu Dr. M.G.R. Medical University (TNMGRMU).

What Are The Common Diagnostic Tests For Heart Attack?

What Are The Common Diagnostic Tests For Heart Attack?

Introduction

Imagine a situation where someone known to you has all the symptoms of a heart attack. If you are not a healthcare professional, you are most likely to either panic or be unaware what needs to be done. The first step is of course to call a hospital for emergency services. Following this, depending on the condition, prescribed medications are to be given, and if trained, you can also give CPR if the patient has lost consciousness or if breathing/pulse has stopped. However, it is important to know about the diagnostic tests for heart attack that the person has to undergo. This will help confirm or rule out a heart attack.

Is a blood test to detect heart attack necessary?

Yes, this is almost always recommended when a person is suspected of having had a heart attack. This is usually performed immediately after an ECG or EKG and is part of the initial diagnostic tests for heart attack. The purpose of a blood test to detect heart attack is mainly to confirm damage to the heart muscle. Typically, there are three types of tests, however, it is always usually the troponin test that is performed by default.

  • Troponin test – This is a test that measures the levels of troponin in the blood sample. Troponin is a protein in the heart muscle, and the levels of this protein in the blood are low, when you are normal. However, if there has been some damage to the heart muscle by way of a heart attack, this protein leaks into the bloodstream, and your troponin levels will increase. When damage is severe, more troponin is released in the blood. This test, therefore, helps to estimate the extent of damage to the heart.

Main reasons for performing blood test as part of diagnostic tests for heart attack.

  • Better diagnosis to indicate heart muscle damage, through reliable sensitivity to heart muscle injury.
  • The high levels of troponin in blood samples will either confirm or rule out a heart attack. For example, angina or gastrointestinal issues are also other possible reasons of chest pain.
  • Extent of damage is assessed through the values in the biomarkers, helping determining the severity of the attack.
  • Gives a sense of urgency to the treatment by helping specialists decide on the type of treatment required.
  • Monitoring outcome of treatment by measuring the biomarkers values in subsequent tests.

Are there occasions when blood tests are not carried out as part of diagnostic tests for heart attack?

Yes, there are specific circumstances, when blood tests are not recommended. For instance, if the patient is known to be very serious condition, requiring CPR or defibrillation, blood tests are skipped. Similarly, if there is a clear clinical diagnosis through ECG findings that confirm a heart, blood tests are skipped.

Can 2D echo detect heart attack?

The answer to this question can only be a nuanced answer, as it is not possible to give a binary answer of yes or no. A 2D echocardiogram helps to assess heart function and also identifies issues that could be related to a heart attack. However, it is always used as a complementary test along with primary diagnostic tests for heart attack. For instance, it is performed along with an electrocardiogram (ECG or EKG) and blood tests.

Before we look at details, it is necessary to note that an echocardiogram and 2D echo are essentially the same. This is a diagnostic test that relies on ultrasound waves to evaluate the heart’s functioning. The echo from waves relay moving images of the heart and valves onto a monitor.  This image is the Echocardiogram, and helps to assess damage due to clots, blockage, or other heart defects.

Can ECG detect heart attack?

Yes, an ECG or electrocardiogram is considered as accurate in diagnosing certain types of heart diseases. However, there are occasions when a person who actually has a condition, will have perfectly normal ECG readings. In such instances, if the treating specialist suspects a heart issue, another ECG or other diagnostic tests for heart attack will be recommended. While the ECG is considered as a primary diagnostic tool, in some cases, you may have to agree to undergo other tests when the results are not conclusive.

How does ECG detect a heart attack?

An ECG works by identifying abnormal patterns in the heart muscle. This is done by attaching small electrodes to the arms, leg and chest. These electrodes measure the electrical signals from the heart and print the signals as lines that are interpreted by the specialist. The different abnormal patterns indicate that the heart muscle is not receiving enough oxygen. This could be due to a blocked artery or due to poor blood supply depriving the muscle of oxygen. One abnormal pattern develops much later, and indicates that death of a portion of the heart muscle.

Why is it necessary to opt for other diagnostic tests for heart attack with an ECG?

There are certain limitations of ECG in detecting a heart attack. For example, if you have a heart attack classified as Silent or Non-ST Elevation Myocardial Infarctions, abnormal patterns will not reflect in an ECG. Another reason is that person may have some existing heart condition or structural defect, and this causes baseline variations. As a result, it makes it difficult to interpret the readings.  Additionally, there is also the possibility of the results turning up false positives or false negatives. This is primarily due to other conditions like pericarditis or any imbalance in electrolytes.

Can oximeter detect heart attack?

No, a pulse oximeter can only offer an indirect indication of a possibility of heart attack. It cannot be considered as a reliable tool to detect heart attack. Though it is true that oxygen saturation and heart rate changes during a heart attack, this is not a confirmed indicator. Let’s understand why a pulse oximeter is a part of the diagnostic tests for heart attack, but not a primary tool.

What happens to oxygen levels and pulse during a heart attack?

When you have a heart attack, your blood oxygenation and pulse rate will change. This is because of the damage to the heart muscle, and the ensuing decrease in blood flow.  Blood oxygen levels are known to come down below 90% during a heart attack. But this is not the case always. At times, the blood oxygen levels are compensated by the body, and as a result there may be no changes in oxygen levels.

What are the primary diagnostic tests for heart attack?

The primary tests that are usually performed to check for a heart attack include the following. However, it is important to note that it is not always necessary for you to undergo all the tests. The actual tests are determined by the symptoms, the medical history of the patient, and findings from initial assessment.

  1. Electrocardiogram (ECG or EKG).
  2. Blood tests – Troponin, Creatine Kinase-MB, Myoglobin.
  3. Chest X-ray.
  4. Echocardiogram.
  5. Coronary Angiography.
  6. Cardiac CT or MRI.
  7. Stress Tests.
  8. Nuclear Imaging.

What is the typical approach to testing?

Typically, the diagnostic tests for heart attack are carried out in the following sequence or approach.

Step #1 – The patient undergoes an initial assessment through electrocardiogram (ECG or EKG), and blood tests to check for troponin levels. The first test is almost always the ECG/EKG, followed by the blood tests.   

Step #2 – In the event of the above two tests showing inconclusive results, and if the specialist suspects a heart attack, you will undergo further evaluation. This includes an echocardiogram or coronary angiography. You may also have to get a chest X-ray, mainly to rule out other reasons of chest pain. The X-ray also helps get a clearer picture of the size and shape of the heart.

Step #3 – For in depth details to determine the best treatment option, it will then be necessary to go in for detailed imaging and other functional tests. This includes a cardiac CT, MRI, or nuclear imaging. In addition to these tests, you may also be put through certain tests to check your heart’s functioning when stressed. However, this is applicable only if you are in a stable condition and in a position to undergo some kind of physical exertion.

The sequence and nature of diagnostic tests for heart attack entirely depend upon certain priorities. For example, the diagnostic value of chosen tests, the condition of the patient, and the time available to take a quick decision are all factors. The whole purpose of protocols and a need-based approach is to accurately and swiftly diagnose a heart attack. This will help in extending the right treatment to mitigate possible damage to the heart and ensure better or desired outcomes.

What is the percentage of risk of heart conditions from genetic predisposition?

Four out of ten people who are at risk of heart attack are people who have inherited the condition. As shocking as it may appear, this is the bare fact about genetic predisposition to heart attacks. Some of the main reasons for heart attack are triggered by what is called as the genetic component. This includes hypertension and atherosclerosis.

How to benefit from genetic testing to check risk of heart attack?

With genetic testing it is possible to actually avoid a situation where you will need diagnostic tests for heart attack. Genetic testing offers actionable information on risk of future heart attacks. This is through identification of certain genetic mutations and variations that are clearly linked to heart diseases.

  • Identification of genetic variants – Certain single nucleotide polymorphisms and genetic variations are identified as linked to increased risk of heart attack. Variations impact lipid metabolism, blood pressure levels, and specific inflammatory responses.
  • Cardiovascular conditions that are passed down the family – Inherited heart conditions predispose people to risk of heart attacks.
  • Medications as per different parameters of individuals – Based on the results, it is possible to opt for individualized treatment plans, and changes in lifestyle. These pre-emptive methods can be changed as per the genetic profile of the individual, that varies from person to person. This offers better, nuanced results.
  • Screening of family members – Genetic testing is ideal for evaluating risk to other family members when someone in the family has the condition. This helps in early detection and helps in chalking out the right steps for preventing.

What conditions are linked to risk of heart attack, that can be uncovered by genetic testing?

The following conditions are linked to a higher risk of heart attack, and can be detected through genetic testing.

  1. Familial Hypercholesterolemia – This is a genetic disorder where the person has high cholesterol levels, resulting in heart disease. This disorder involves three different genes.
  2. Hypertrophic Cardiomyopathy – Patients with this condition end up with abnormally thickened heart muscles. This increases the burden on the heart when pumping blood. This disorder also involves three different genes.
  3. Long QT Syndrome – This is a condition affecting the heart’s electrical activity causing acute, uncontrollable, and life endangering irregular heartbeats. The number of genes involved in this condition are three.
  4. Marfan syndrome – This refers to a connective tissue disorder that results in the formation of bulges in the artery. Known as aortic aneurysm, this considerably increases the risk of heart attack and involves one gene.
  5. Brugada syndrome – This condition affects ECG findings, increasing the risk of fatal heart disease. This condition involves one gene.  
  • Polygenic risk factors – This refers to various genes that contribute to the risk of heart attack, due to the collective effects of the genetic variations. The test calculates the cumulative polygenic risk scores to quantify the risk of heart disease.

Is genetic testing for heart attack risk available in Tamilnadu?

Yes, genetic testing for future risk of heart attack due to genetic factors is presently available in Tamilnadu. The testing protocol and the timeline of the testing, analysis and results are outlined below.

#1 You will undergo pre-test counseling to understand all about the tests, its limitations and its implications.  

#2 You will provide a sample of either your blood or saliva for DNA extraction. This takes a few minutes at the maximum.

#3 The sample is then analyzed in a laboratory to identify variations in genes. This analysis could sometimes run into a few weeks, between 2 weeks to 6 weeks.

#4 Following the analysis, the healthcare provider explains the outcomes of the results over a single session.

Avoid the future need of undergoing diagnostic tests for heart attack by checking your genetic predisposition. This ensures early intervention, and minimizes your risk of heart ailments, apart from avoiding extended hospitalization and the time for recovery from an attack.

Medically Reviewed by

Dr.Rajasekar Cardiologist

Dr. Rajasekar is a cardiologist in Chennai, with extensive experience in the field. He completed his MBBS from Madurai Kamaraj University, followed by an MD in General Medicine and a DM in Cardiology from The Tamil Nadu Dr. M.G.R. Medical University (TNMGRMU).

Heart attack And Its Relationship With Cholesterol Buildup

Heart attack And Its Relationship With Cholesterol Buildup

Introduction

Data released by the World Health Organization shows that around 27% of deaths in India are due to cardiovascular diseases. This means that one in four deaths is due to heart conditions. This needs to be read in the context of a recent survey which found that 39% of respondents who had high cholesterol also had heart diseases. Read on to understand more about heart attack and its relationship with cholesterol levels.

Does cholesterol cause heart attack?

Yes, high levels of cholesterol plays a significant contributing factor to risk of heart attack. Before we look at other information and statistics, here is something that you should know, something that needs to have high recall value. 

Ideal cholesterol levels

There are four different types of cholesterol values that are considered during diagnostics – total cholesterol, non-HDL, LDL and HDL. These are the reference values that indicate that your cholesterol levels are normal and not high.

  • If you are 19 years or younger, your total cholesterol should be less than 170 mg/dl. Non-HDL should be less than 120 mg/dl, LDL should be less than 100 mg/dl, and HDL should be more than 45 mg/dl.
  • If you are male above 20 years, your total cholesterol should be between 125–200 mg/dl. Non-HDL should be less than 130 mg/dl, LDL should be less than 100 mg/dl, and HDL should be more than 40 mg/dl.
  • If you are a female above 20 years, your total cholesterol should be between 125–200 mg/dl. Non-HDL should be less than 130 mg/dl, LDL should be less than 100 mg/dl, and HDL should be more than 50 mg/dl.

     

Now, lets return to the main focus, that is heart attack and its relationship with cholesterol. It is an acknowledged fact that high levels of LDL, or “bad” cholesterol, is linked to a higher risk of heart disease.  However, this should not cause alarm, as the severity of a heart attack depends on several factors. For example, the location and extent of blockage, the time between attack and treatment, and overall heart health.

It is also necessary to add here that heart attacks caused by high cholesterol are serious, but these attacks are not always the most severe in nature. To understand this, it is necessary to learn more about the different types of heart attacks and respective severity levels.

  1. ST-Segment Elevation Myocardial Infarction (STEMI) – This is the most severe type among heart attacks. This is due to a complete blockage of a coronary artery. The patient is to receive immediate treatment to ensure blood flow and to reduce any damage to the heart. Symptoms include severe pain in the chest, difficulty breathing, feelings of nausea, and excessive sweating.
  2. Non-ST-Segment Elevation Myocardial Infarction (NSTEMI) – This is classified as next in severity and is due to a partial block of a coronary artery. This require urgent treatment, though it is not as dangerous as the previous attack. Symptoms are similar to the previous type but not intense. 
  • Silent Heart Attack – As a result of the absence of symptoms, the extent of damage depends on the time of detection and treatment. This makes the severity variable.

     

Heart attacks attributed to cholesterol levels

Here is additional information about heart attack and its relationship with cholesterol. High levels of LDL cholesterol can result in an abnormal build of plaque in the coronary arteries. This, in turn, can cause blockages which could end up in heart attacks. This could be either types of heart attacks – STEMI or NSTEMI.

What is the severity of heart attacks caused by high cholesterol levels?

The severity of heart attacks due to cholesterol depend on the type of blockage. For instance, if a large artery is fully blocked, this could cause STEMI, and this is highest in terms of severity. However, if the blockage is partial, this causes NSTEMI, with moderate to high severity, and lesser than STEMI.

Are there any distinct symptoms of a heart attack due to cholesterol?

No, there are no exclusive or different symptoms in heart attacks despite the relationship with cholesterol. Symptoms due to cholesterol buildup are similar to other reasons for heart attacks. This is because the underlying actions are the same, that is restricted blood flow to the heart muscle.  

Here is a look at the symptoms of a heart attack

You may experience any of these common symptoms, such as:

  • Pain in the chest or some kind of discomfort.
  • An abnormal squeezing sensation or extreme pressure and pain in the upper part of the body.
  • Difficulty breathing may be experienced with or without any chest discomfort.  
  • Pain in the upper torso could be either or both arms, upper back, the neck, jaw, or stomach.
  • Symptoms such as feelings of nausea, indigestion or heartburn, or pain in the abdomen are also common. 
  • Cold sweat.
  • Abnormal tiredness. 
  • Fainting or lightheadedness.

     

Women experience symptoms that are sometimes different. This often results in confusion as some other reason, and includes:

  • Overall tiredness. 
  • Disturbed sleep.
  • Feelings of anxiety.
  • Lightheaded feeling.
  • Back pain, jaw pain.

Detailed look at cholesterol

To understand heart attack and its relationship with cholesterol better, it is necessary to know more about cholesterol, beginning with the different types of cholesterol.

LDL, short for Low-Density Lipoprotein – This is commonly labelled as “bad” cholesterol and results in the buildup of plaques in the arteries. This causes atherosclerosis, narrowing and hardening the arteries. 

HDL, short for High-Density Lipoprotein – Labelled as “good” cholesterol, this removes LDL cholesterol from the bloods. You need to have higher levels of HDL, to reduce your risk of a heart attack.

Triglycerides – A type of fat in the blood, this can also contribute to atherosclerosis if the levels are high.

Is cholesterol inherited genetically?

Yes, cholesterol levels are known to be genetically inherited. If a member of your family has high cholesterol levels, you could also be at risk of having high cholesterol. With the above information about heart attack and its relationship with cholesterol, it is also important to learn about the genetic component.  Various genetic factors affect cholesterol levels, including the following. 

  1. Familial Hypercholesterolemia.
  2. Polygenic Hypercholesterolemia.

Will genetic testing reduce the risk?

Yes, genetic testing can reduce the risk of complications later in life. This is by identifying mutations that impact cholesterol levels. When viewed with detailed family history, it can identify your risk levels.

How to manage heart attack risks after genetic testing?

If you have genetically inherited high cholesterol levels, you can choose the following options. This will help reduce the risk of heart attack by its relationship with cholesterol.

  • Lifestyle changes like a healthy diet, regular exercise and quitting smoking.
  • Medications like statins, ezetimibe, or PCSK9 inhibitors.

Before winding up, let’s look at the timeline of cholesterol buildup.

  1. People who are genetically predisposed may have cholesterol buildup as early as childhood.
  2.  People who are genetically predisposed may also experience cholesterol buildup in young adulthood.

Medically Reviewed by
Dr.Rajasekar Cardiologist

Dr. Rajasekar is a cardiologist in Chennai, with extensive experience in the field. He completed his MBBS from Madurai Kamaraj University, followed by an MD in General Medicine and a DM in Cardiology from The Tamil Nadu Dr. M.G.R. Medical University (TNMGRMU).

Understanding Heart Attack Causes Through Advanced Genetic Testing

Understanding Heart Attack Causes Through Advanced Genetic Testing

Introduction

Did you known that one in ten people in cities in India, have heart ailments? Yes, prevalence is as high as 13% in urban areas. There is hope however, as statistics also state that 90% of heart attacks can be prevented with timely diagnosis and the right treatment. The question is, is it possible for you to learn before a heart attack occurs that you may get one? Yes, certain causes of heart attack can be predicted through genetic testing. Let’s step back to see one of the most famous quotes of medical science by Hippocrates, the father of modern medicine. It is more important to know what sort of person has a disease than to know what sort of disease a person has. Treatment is effective after clearly understanding heart attack causes; here is a quick look at the major reasons for heart attacks.

What is the cause of heart attack ?

Also known as myocardial infarctions, the cause of heart attack is blockage of the flow of oxygen-rich blood to your heart muscle. Left untreated, this causes either damage to the affected heart muscle or death of the heart muscle. This is the main cause of heart attack, and there are multiple underlying factors or health conditions that build up to this stage. In South India, it is now possible to check for underlying health conditions, through genetic testing. The following list of conditions help in understanding heart attack causes better.

  • Coronary Artery Disease – Commonly known as CAD, this is identified as the most common cause of heart attacks. This is attributed to a narrowing or blockage of the coronary arteries that carry blood to the heart muscle. This narrowing or blockage is due to a buildup of cholesterol and plaque. This buildup is known as atherosclerosis. Plaque refers to substances that contain the following:
  1.  Cholesterol – High levels of LDL, also known as “bad” cholesterol cause formation of plaque.
  2.  Fatty deposits – This refers to accumulation of lipid which results in the thickening of artery walls.
  3. Calcium – Build-up of calcium in the plaque, causes hardening and increased narrowing of the arteries.
  4. Cellular waste – Plaque also often contains waste from cells.
  5. Fibrin – This is clotting material released in the body to repair damaged vessel walls.
  6. Plaque rupture – The plaque in the coronary artery can possibly rupture, causing the formation of a blood clot. This blood clot can ultimately obstruct the flow of blood to the heart muscle, causing a heart attack.
  7. Coronary artery spasm – This refers to a temporary, highly intense spasm of a coronary artery. This can either decrease the flow of blood or stop the flow of blood to a section of the heart muscle. This is possible in arteries that are either free from plaque buildup and arteries that are affected by atherosclerosis. While the reasons are not fully clear, it is linked to drug abuse, stress, and lifestyle factors like smoking.
 

What are the common risk factors that increase the chances of getting a heart attack?

There are multiple risk factors that increase your possibility of having a heart attack. The following conditions help in understanding heart attack causesIn south India, there are advanced genetic testing facilities to identify risk factors an the possibility of a heart attack in the future.

  1.  High blood pressure – Medically known as hypertension, this increase the strain on the heart and arteries.
  2. High cholesterol levels – When there are high levels of low-density lipoprotein cholesterol, there is an increased risk of atherosclerosis.
  3. Smoking – This causes significant damage to the lining of arteries. This also makes it conducive for the formation of blood clots.
  4. Diabetes – High blood sugar levels cause damage to the blood vessels, and contribute to high risk of heart disease.
  5. Obesity – This is a condition that is generally linked to high blood pressure, diabetes, and high cholesterol. All these three causative factors increase risk of heart attack.
  6. Sedentary lifestyle – Inadequate physical activity can lead to obesity and exposure to other risk factors.
  7. Poor diet – A diet that is rich or high in saturated fats, trans fats, cholesterol, and sodium exposes the person to risk of heart disease.
  8. Family history – A major factor of heart disease is genetic predisposition.
  9. Age and gender – Older men and women are at higher risk of the condition. Among genders, men are more at risk; and this is at an earlier age compared to women.
  10. Stress: Another reason that most people fail to notice is the effect of chronic stress. This can increase the risk of heart attack through higher heart beat rate and blood pressure.
  11.  Alcohol – People who over indulge in alcohol may end up with higher blood pressure levels. This can lead to other factors that increase risk of heart disease.

How does plaque formation result in heart attacks ?

The formation of plaque results in possible heart attack due to the following conditions:

  •  Narrowing of arteries: When plaque builds up, it cause a narrowing of the coronary arteries. This reduces the flow of oxygen-rich blood to the heart. This results in the person experiencing chest pain during some physical activity. 
  •  Plaque rupture: The built up plaque can rupture, and this ends up as a blood clot. When the body tries to heal, it could possible fully block the artery.

What is the cause of heart attack at young age?

There are many reasons for heart attack at a young age, and this makes it necessary for timely screening and treatment. The known average age of heart attacks in India is 50 for men and 55 for women. However, the Indian Heart Association clarifies that 50% of these attacks are in men below the age of 50, and 25% below the age of 40.

This effectively means that the younger generation is prone to heart attacks. This is unlike the previously held belief that heart attacks are only experienced by the older generation. Let’s look at the conditions below for understanding heart attack causes in young people. If you are apprehensive of risks of a heart attack, there are advanced genetic testing options available in south India to identify risks.

Genetic predisposition

  • Familial hypercholesterolemia – This refers to inherited condition where young people have very high levels of LDL cholesterol. This puts the person at risk of early-onset coronary artery disease.
  • Genetic mutations – Certain genetic mutations impact the way the body works. For example, lipid metabolism, blood clotting, and regulation of blood pressure change with certain mutations.

     
Lifestyle Factors

  • Smoking – This is a serious risk factor for heart disease, contributing to atherosclerosis.
  • Substance abuse – Drugs and substances such as cocaine, amphetamines, etc., are known to increase risk. Coronary artery spasm, increased heart rate, and high blood pressure, are possible outcomes of abuse. This in turn can result in risk of heart attacks.
  • Unhealthy diet – A diet that is rich or high in saturated fats, trans fats, and cholesterol can result in plaque formation.

   
Medical conditions

  • Diabetes – Type 1 and type 2 diabetes.
  • Hypertension.
  • Obesity.

 
Inflammatory conditions

  • Autoimmune diseases – Certain conditions like lupus and rheumatoid arthritis put young people at increased risk. This includes atherosclerosis and heart attacks as a result of chronic inflammation.
  • Infections – Specific viral or bacterial infections are known to bring about inflammation of the heart or blood vessels. This can, in turn result in cardiovascular events.

 
Physical stress

  • Extreme activity – When there is intense physical activity undertaken suddenly, there is a risk of heart attack. This is especially among people with underlying heart conditions.
  •  Severe emotional stress – Stress cardiomyopathy refers to severe emotional stress. Also known as broken heart syndrome, this condition is similar to that of a heart attack.

   
Congenital heart defects

  • Certain structural heart abnormalities at birth can increase the risk of heart attacks in young people. 

    Premature atherosclerosis

  • This is possible in young individuals due to many reasons. This includes genetic factors, metabolic disorders, or lifestyle. These can contribute to premature atherosclerosis, resulting in heart attacks.

Some of the causes of heart attack in women are common to both men and women, while some are more specific to women. Conditions that are specific or more prevalent among women include the following. This will help in understanding heart attack causes in women. You can look for possible future risks of heart attack through genetic testing options in Tamilnadu.

  • Prinzmetal’s Angina – This refers to temporary spasms in the coronary arteries. This decreases the flow of blood to the heart, resulting in chest pain and possible heart attacks.  
  • Microvascular disease – Coronary microvascular dysfunction- This refers to a condition where the small vessels in the heart are either damaged or do not function properly. This results in reduced blood flow and is known as small vessel disease. 
  • Spontaneous coronary artery dissection – Tear in coronary artery – When a tear occurs in the coronary artery wall, blood flows between the different layers of the artery wall. This results in a heart attack and this SCAD is more prevalent in younger women. Unfortunately, this can affect women who do not have any other normal risk factors.

 

Risk factors in women 

As can be seen from the above, certain conditions are specific to women. This is apart from the conditions that are common to both men and women. The following risk factors are specific to women.

Hormones.

  • Menopause – A decrease in levels of estrogen post-menopause can increase the risk of heart conditions in women.
  • Pregnancy – Certain conditions are related to pregnancy, like preeclampsia, gestational diabetes, and hypertension. This increases the risk of heart disease in women at some later period in life.

Autoimmune conditions – Certain autoimmune diseases like lupus and rheumatoid arthritis are more common among women. These conditions are linked to an increased risk of heart disease.

Mental health – Due to increased depression and anxiety, women are exposed to the risk of heart ailments.

  • Diabetes – Women with diabetes are exposed to a higher risk of heart disease.
  • Women who smoke are at increased risk of developing heart disease. 

What are the causes of silent heart attack ?

The causes for a silent heart attack are mostly similar to that of a typical heart attack. The difference is in the symptoms. A typical heart attack is known as a symptomatic heart attack or recognized myocardial infarction. A silent heart attack is known as a silent myocardial infarction. A typical heart attack has noticeable symptoms like:

  • Chest pain.
  • Some kind of discomfort.
  • Shortness of breath.
  • Feelings of nausea.
  • Lightheadedness.
  • Sweating.
  • Pain in upper body – arms, back, neck, or jaw.

     

 A silent heart attack has minimum symptoms and is mostly detected when tests are undertaken. This includes electrocardiogram, or blood tests undertaken for other conditions. Mild symptoms that actually indicate but are difficult to be recognized as a heart attack include:

  •  Fatigue.
  • Shortness of breath.
  •  Indigestion.
  •  Discomfort in the chest, back, arms, or jaw.

Causes of silent heart attack

The causes for both types of heart attack are usually similar. The following list of conditions help in understanding heart attack causes and risks and better. If you are in doubt about possible risks of a silent heart attack, avail genetic testing options in Tamilnadu to check for possible causes.

  • Coronary artery disease.
  • Smoking.
  • High blood pressure.
  • High cholesterol levels.
  • Diabetes.
  • Obesity,
  • Family history.

People are at higher risk of silent heart attack due to specific factors like diabetes and neuropathy. The reasons are mostly the same, the treatment is also similar. The main difference is in the manner in which symptoms are experienced.

Genetic testing and the ability to detect conditions

Through simple genetic testing, it is possible to uncover the genetic component of risk of heart attacks. This applies to people who are at risk of heart attack at a young age, people at risk of a silent heart attack and women at risk of a heart attack. Genetic testing helps in understanding heart attack causes and risks, through the following: 

  •       Identifying familial genetic conditions.
  •       Personalized risk assessment.
  •       Detecting rare genetic variants.
  •       Family screening.

It is important to note that genetic component of heart attack risk is one of many factors. Testing will help identify these risks. A comprehensive evaluation will help look at other components.

How is genetic testing for heart attack carried out?

Genetic testing involves a few simple steps in sequence to identify genetic variants linked to increased risk of heart disease. The entire process could take days or a few weeks to complete. It begins with an evaluation followed by sample collection, which could be either blood sample or saliva.

The evaluation may require one or two sessions, and the sample collection takes minutes to complete. The collected sample is then sent to a laboratory for analysis. This may take days to complete, depending on the type of tests recommended. The test data is then analysed and interpreted, which could take a few days to conclude. Based on the results, the detected condition is then managed and this includes use of medications, changes in lifestyle and family screening. These tests are an ideal way to detect unknown risks and help you in understanding heart attack causes that may cause a possible attack in the future.

Medically Reviewed by
Dr.Rajasekar Cardiologist


Dr. Rajasekar is a cardiologist in Chennai, with extensive experience in the field. He completed his MBBS from Madurai Kamaraj University, followed by an MD in General Medicine and a DM in Cardiology from The Tamil Nadu Dr. M.G.R. Medical University (TNMGRMU).

Are Heart Attack Symptoms And Triggers The Same For Everyone?

Are Heart Attack Symptoms And Triggers The Same For Everyone?

Introduction

Variations in symptoms and triggers of heart attacks are a fact and should not be overlooked. There is the possibility where you may end up not recognizing a real symptom due to wrong assumptions. These variations extend across gender, age, and health conditions. However, there are certain common “tell-tale” heart attack symptoms and triggers that can help identify and take suitable action. Let’s decode the symptoms and the triggers that can help you make the right decision for timely intervention.

What experiences do survivors have of heart attack symptoms and triggers?

Here are first hand accounts of survivors of heart attacks. Learn of the different symptoms and experiences recounted by survivors. 

  1. A man aged 60, used to experience some kind of stabbing pain in the back during certain actions like climbing up or down stairs. He also experienced indigestion, and a squeezing sensation on his heart. These were symptoms that he ignored, which were building up within him. One night, he felt uneasy before dinner, he felt feverish, even though his body temperature was normal. He then experienced indigestion. Finally, when he experienced a severe crushing sensation in his heart, he realized he was having a heart attack. He was rushed to hospital, underwent an open heart surgery, survived, and lived to tell his story.
  2. A lady aged 62 experienced a full feeling in her stomach despite not having overeaten. She then experienced a tightness in her chest and was short of breath. The symptoms seemed to have reduced, and she slept over it. However, the symptoms increased later, and she was rushed to a hospital. She was diagnosed with a blockage in her artery, and after treatment is now leading a near-normal life.

There are multiple examples of different types of heart attack symptoms and triggers that clearly show the importance of awareness. Here is a look at some of the common symptoms.

  1. Pain or discomfort in the chest – This could be some kind of squeezing sensation, pressure or pain right in the middle of the chest. This usually lasts for a few minutes, and can sometimes reduce to return later. 
  2. Discomfort in the upper part of the body – If you have any abnormal pain or discomfort in your arms, in the back, your neck or jaw, you need to look for other symptoms or triggers. 
  3. Difficulty breathing – This may occur with or without any discomfort in the chest and during physical activity or while resting. 
  4. Breaking into a cold sweat – If you are experiencing any abnormal cold sweat, beware, it could also indicate heart attack symptoms and triggers, if other factors contribute to a heart attack.
  5. Feelings of nausea and possible vomiting – There could be a sudden feeling of nausea with or without vomiting. 
  6. A lightheaded or dizzy feeling – Some people are known to feel faint or experience a passing out sensation, and this is also a possible symptom of a heart attack.
  7. Overall tiredness – Women may experience extended periods of fatigue.

Is the information true about the pressure point in thumb that causes heart attack?

No, this is a misconception and is to be ignored totally. People who believe these unscientific or unproven claims are likely to end up with problems. Certain alternative therapies make wild claims that are not backed or supported by evidence.  Any ignorance about the real heart attack symptoms and triggers and effective treatment can cost lives. In certain alternative medicine practice, pressure points are used to relieve pain and to help overcome some discomfort.

However, this can in no way offer relief or be considered as treatment in the event of heart attack. The reasons for a heart attack are different from that of usual pain. The cause of a heart attack are also totally different. It is just not possible for pressure points to help offer relief.

What are the common sudden heart attack causes?

Some of the conditions identified as reasons for sudden heart attack include the following. This will help you understand heart attack symptoms and triggers better.

  • Coronary artery disease – When cholesterol and other fatty deposits clog the arteries, blood flow to the heart is reduced, and this can cause a sudden heart attack.
  • Cardiomyopathy – This refers to a condition when the heart is enlarged, as a result of the walls in the heart stretching. In such conditions, the muscles in the heart become bigger, and this could cause a sudden heart attack.
  • Heart valve disease – When the heart valves narrow, it can result in a thickening of the heart muscle. Similarly, if the heart valves leak and cause the chambers to enlarge, it could affect the rhythm. These conditions can cause a sudden heart attack.
  • Congenital heart problems – Children born with a heart problem are likely to get a sudden heart attack during adolescence. This could also occur in adults who have undergone surgical procedures for congenital heart problems. 
  • Long QT syndrome – This belongs to the category of heart signaling problems. This causes the heart to beat abnormally. When the heart beat rhythm does not return to normal, this can cause a sudden heart attack.

What you can do to identify and prevent or reduce the effects of heart attacks?

An awareness of the different heart attack symptoms and triggers is necessary, Especially, the different variations in symptoms and triggers need to be known. More importantly, it would be a good idea to undergo the right tests that help to identify a person’s genetic predisposition to heart attacks. There are multiple reasons or causes for a heart attack. One of the reasons or causes is a person’s genetic possibility of getting a heart attack.

With simple genetic testing, you can now learn if you are likely to get a heart attack later in life, due to any genetic reasons. This will considerably help you reduce the risk of getting a heart attack. This will also help you modify your lifestyle, and take suitable pre-emptive treatment. This will increase your chances of survival and also help you live healthier. Tamilnadu now has advanced genetic testing facilities, that offer clients a proven and simple option for a detailed analysis.

Medically Reviewed by

Dr.Rajasekar Cardiologist

Dr. Rajasekar is a cardiologist in Chennai, with extensive experience in the field. He completed his MBBS from Madurai Kamaraj University, followed by an MD in General Medicine and a DM in Cardiology from The Tamil Nadu Dr. M.G.R. Medical University (TNMGRMU).

 

How To Survive Effects Of Blood Pressure On Heart Attack?

How To Survive Effects Of Blood Pressure On Heart Attack?

Introduction

Hypertension is linked to 13% of all deaths all over the world. This essentially means that one out of ten deaths is due to blood pressure. It is well established that hypertension greatly increases the risk of various cardiovascular conditions. This includes heart attacks, heart failure, and strokes and the impact is due to various effects it cause on the body. Let’s look at the effects of blood pressure on heart health and the various options available in Tamil Nadu to detect risk of hypertension.

Does high bp cause heart attack?

Yes, high blood pressure contributes to high risk of heart attack. Two of the most renowned ogranisations – the World Health Organisation, and the American Heart Association support this finding. Hypertension is the leading cause of heart attacks and other cardiovascular diseases. Listed below are some of the effects of blood pressure on heart disease.

Damage to the arteries and atherosclerosis

High blood pressure is known to bring about excessive force on the walls of arteries. This, in turn, causes damage to your arteries over a period of time, if left untreated. For instance, the inner lining of your arteries may be exposed to higher risk of buildup of fatty deposits.  Atherosclerosis refers to the buildup of plaque. The damage caused to your arteries, can result in atherosclerosis, narrowing the arteries, and reducing the flow of blood to the heart.

Strain on the heart

As a result of high blood pressure, the workload on your heart increases. The heart ends up having to pump harder to efficiently circulate blood. This increase in workload causes thickening of the heart muscle, and this weakens your heart over a period of time. This affects the ability of the heart to pump blood as required. This condition may eventually result in heart failure.

Sudden and severe coronary events

The plaque formed in your arteries can rupture, and this results in formation of blood clots. When a blood clot fully blocks a coronary artery, the flow of blood to your heart muscle stops. This causes a heart attack, and is known as myocardial infarction.

These are the effects of blood pressure on your heart health and pose considerable risks of heart attack. The silver lining is that you can detect the possible risk of blood pressure and heart attack through genetic testing. If you are a resident of Tamil Nadu, avail of genetic testing facilities to quickly and conclusively detect any future risk of heart attacks.

What are the values of blood pressure and when is it known as high blood pressure?

There are different categories of blood pressure based on the values. This includes the following:

Normal

  • Systolic – Lesser than 120 mm Hg
  • Diastolic – Lesser than 80 mm Hg

     

Elevated

  • Systolic – 120-129 mm Hg
  • Diastolic – Lesser than 80 mm Hg

     

Stage 1 Hypertension 

  • Systolic – 130-139 mm Hg
  • Diastolic – 80-89 mm Hg

     

Stage 2 Hypertension

  • Systolic – 140 mm Hg or higher
  • Diastolic – 90 mm Hg or higher

     

Hypertensive crisis  

  • Systolic – Higher than 180 mm Hg
  • Diastolic – Higher than 120 mm Hg

Does low bp cause heart attack?

Not directly, but low blood pressure can be linked to risk of heart attack risk in some specific conditions. Lets look at the effects of blood pressure on heart health, in the context of low blood pressure. This is known as hypotension and the values that are considered as low blood pressure are:

  • Systolic – Lesser than 90 mm Hg
  • Diastolic – Lesser than 60 mm Hg

The following conditions contribute to or cause risk of heart attack

Lesser flow of blood to the heart

Known as coronary perfusion, this is due to very low blood pressure. This reduces blood flow to the coronary arteries. This reduced blood supply can cause chest pain, known as angina or myocardial infarction, when oxygen does not reach the heart muscle for some time.

Existing health conditions

A person who is diagnosed with possible risk of heart conditions will be at higher risk, due to severe hypotension.  Similarly, a person who suffers from cardiogenic shock or septic shock due to infection can end up with very low blood pressure levels. This can result in damage to the heart or heart attack.

Medicines and excessive treatment for high blood pressure

If you are hypertensive, you are likely to be on antihypertensive medications. Ensure that you do not treat the condition with excessive medications. This can reduce blood pressure levels, causing reduced blood flow to the coronary arteries, increasing risk of heart attack. 

Similarly, if you are diuretics or medicines that lower blood pressure, you may be at risk of hypotension and possible heart attack.

Are there any other effects of blood pressure on risk of heart attack

Yes, there are a few indirect effects of blood pressure and risks of heart attack. For example, severe dehydration can cause hypotension and bring down blood volume. This may affect heart function negatively, and increase risk of possible heart conditions. 

Similarly, blood loss that is severe and high from injury or surgery can result in hypotension. This can reduce delivery of oxygen to the heart muscle, increasing risk of heart conditions.

Testing facilities in Tamil Nadu to detect genetic factors that may cause high blood pressure

Advanced testing facilities are presently available in Tamil Nadu to help detect if you are genetically predisposed to developing high blood pressure. For example, there are specific genetic variants that are linked to an increased risk of developing high blood pressure.

This affects the manner in which your body regulates blood pressure through the kidneys, blood vessels, hormones, and the sympathetic nervous system. Genetic testing can help identify various genetic markers that are linked to hypertension. Variants in the genes AGT, ACE, and CYP11B2 are associated with blood pressure regulation, and by detecting this, it is possible to understand your risk of hypertension.

Polygenic Risk Scores, abbreviated as PRS can clearly indicate if you have a higher or lower probability of developing hypertension. When viewed along with other diagnostic tests, it is possible to detect your risk of blood pressure, and further risks of heart attacks.

Medically Reviewed by

Dr.Rajasekar Cardiologist

Dr. Rajasekar is a cardiologist in Chennai, with extensive experience in the field. He completed his MBBS from Madurai Kamaraj University, followed by an MD in General Medicine and a DM in Cardiology from The Tamil Nadu Dr. M.G.R. Medical University (TNMGRMU).

How To Avoid Heart Attack Through Preventive Health Options?

How To Avoid Heart Attack Through Preventive Health Options?

Introduction

India witnessed a 12.5% increase in fatal heart attacks, as per government records. Unknown to a lot of people, studies indicate that South Indians have a higher risk of coronary artery disease than North Indians[1]. Advances in medical science now make it possible to identify risk of heart attack with a small sample of blood or saliva. Learn how to avoid heart attack through simple preventive health options that can now help reduce your risk of an attack.

What causes heart attack?

Before you look at preventive health and how to avoid heart attack, here’s a quick summary about the reasons for heart attacks. Medically known as a myocardial infarction, heart attacks are mainly due to a blockage in the arteries that take oxygen-rich blood to the heart. As a result of these blockages that either reduce or fully cut off supply, the heart undergoes damage. 

Reasons for blockage are typically due to buildup of fatty deposits on the walls of the arteries. Known as atherosclerosis, this is a progressive condition, that slowly builds up over time. Eventually, the plaque may rupture, forming blood clots that can block the artery if large enough, causing a heart attack.

If you have any of the following conditions, it may possibly contribute to atherosclerosis:

  • High blood pressure levels.
  • High cholesterol levels.
  •  Diabetes.
  • Lifestyle – smoking, obesity, lack of exercise, stress.
  • Inherited – history of heart disease in family.
  • Age, gender.

 

Avoid heart attack by learning if you are predisposed and at higher risk of an attack

CAD, coronary heart disease is known as a “silent killer”, because the underlying condition often develops slowly. This occurs without noticeable symptoms, or the symptoms may be infrequent or mild, and if you have the condition, you are most likely to dismiss the symptoms. The whole concept of genetic testing is simple – you submit a sample, and learn if you are predisposed genetically to heart disease. Armed with this information, your specialist can help you with information on how to avoid heart attack.

The test involves analyzing millions of variants in DNA from the saliva sample through genotyping. Gene variants are identified along with the number of copies of gene variants. On the basis of these numbers, the risk of possible heart attack is calculated. For example, some gene variants are linked to cholesterol metabolism, blood clotting, function of the blood vessels, and inflammation.

This gives you a personalized risk assessment of possible heart attack. On the basis of this assessed risk, you can then follow the cardiologist’s recommendations for preventive measures and how to avoid heart attack. The question is – is this method effective? These genetic testing methods have been accepted as promising by authoritative sources, for example, the American Heart Association.

Will preventive methods help avoid heart attack?

Yes, preventive measures are proven as effective. Studies have clearly demonstrated the efficacy of preventive methods through lifestyle changes and medical intervention. Some of the common preventive methods include:

  • Manage underlying conditions that contribute to risk of heart attack.
  • Medications to manage high blood pressure, high cholesterol, diabetes.
  • Medications like aspirin, antiplatelet drugs.
  •  Changes in lifestyle – smoking cessation, controlled diet, routine minimum physical activity.
  • Periodic monitoring.

 

What is the procedure for genetic testing for risk of heart attack?

The procedure is simple and requires just a few minutes of time. You will be asked to provide a sample of saliva. A special saliva collection kit is used for collecting this sample. You will be asked to either spit into a tube, or the saliva is collected through a swab of the inside of your cheek.

The DNA is then extracted or isolated, following which it is analyzed through genotyping. After the results are interpreted, depending on the score, you will undergo follow-up treatment.

Compelling advantages that make genetic testing a great and revolutionary option

The nature of the disease makes it imperative to be aware of possible risks. The American Heart Association claims that 90% of cardiovascular conditions can be prevented through certain actions. However, before you learn how to avoid heart attack, it is important learn about the possible risks. Predictive genetic testing can also help you with info on how to avoid heart attack while sleeping.

Genetic testing for conditions can be considered as useful, when certain criteria are fulfilled. For instance, testing is meaningful, when preventive or treatment options are available. With heart attacks, there are clear preventive options that help to reduce the risk. This makes genetic testing suitable for detecting and helping prevent your risk of heart attacks.

What are the symptoms of atherosclerosis?

The symptoms of atherosclerosis help to understand the urgency of the need for treatment and help avoid heart attack. Common symptoms include the following:

  1. Angina – Pain in the chest or discomfort experienced like abnormal pressure, or a squeezing sensation. Any tightness of heaviness in the chest that spreads to the shoulders and arms is also a possible indication.
  2. PAD, acronym for peripheral artery diseases – Pain in the leg, weak or numb sensation could be an indication of PAD.
  3. Carotid artery disease – Any sudden weak or numb sensation in the face, limbs or one side of the body can indicate the condition. Individuals may find it difficult to speak clearly or comprehend.
  4. CAD, acronym for coronary artery disease – Pain or discomfort in the chest, difficulty breathing, overall weakness are some symptoms of CAD.
  5. Renal artery disease – Hypertension, or impaired functioning of the kidneys.
  6. Abdominal aortic aneurysm – Pain in the abdomen or back, feeling full even after small meals. Individuals are likely to feel a strange sensation in the abdomen like a pulsating feeling.

Polygenic risk score through genetic testing helps understand future risk of heart attack

The polygenic risk score (PRS), gives a clear risk score on predisposition to possible heart attack. Based on genetic variants determined through analysis of saliva sample, this identifies the probability of future risk of heart attack in individuals. To learn more about how to avoid heart attack, genetic testing, or seek clarifications from an expert, click here for a quick response.

Medically Reviewed by

Dr.Rajasekar Cardiologist

Dr. Rajasekar is a cardiologist in Chennai, with extensive experience in the field. He completed his MBBS from Madurai Kamaraj University, followed by an MD in General Medicine and a DM in Cardiology from The Tamil Nadu Dr. M.G.R. Medical University (TNMGRMU).

Giving Wings To Your Kids Future

Giving Wings To Your Kids Future

Introduction

Parenting is a journey of endless possibilities. It is a sacred trust bestowed upon us to nurture, guide, and empower the next generation.  

While embarking on this odyssey, the greatest aspiration is to give children the wings to soar. It also helps to embrace their passions. For carving out their destinies amidst the boundless sky of opportunity. 

Cultivating a Growth Mindset Planting Seeds of Resilience

At the heart of nurturing children’s future lies the cultivation of a growth mindset. It is a belief that is about innating the capacity to learn, grow, and adapt in the face of challenges. Further instilling resilience, perseverance, and a hunger for knowledge. Let’s equip them with the tools to navigate the twists and turns of life’s journey with courage and grace. 

Encourage curiosity, experimentation, and a willingness while embracing failure as a steppingstone towards success.  

Teach them to have a proper setback while roadblocks but it shall further detour on the path to greatness, and that the pursuit of excellence. It goes well as per the lifelong journey of discovery and self-improvement.

Fostering a Love of Learning Igniting the Spark of Passion

Education is the cornerstone of a bright and promising future. But the truth about learning extends far beyond the confines of the classroom.  

Nurture the child’s natural curiosity and interests, while exposing them to a rich tapestry of experiences that ignite some of the passion and fuel proper imagination. 

Encourage exploration in diverse fields. Right from science and literature to art and music—and celebrate the unique talents and strengths.  

Foster a love of learning that transcends grades and accolades and instills in them a lifelong thirst for knowledge and self-discovery.

Embracing Creativity Unleashing the Power of Imagination

In a world driven by innovation and change, creativity shall emerge as a powerful force for shaping the future.  

Encourage the child to think outside the box, while dreaming some of the boldly, and to unleash the boundless power of their imagination. 

Provide opportunities for self-expression through art, storytelling, and imaginative play, and celebrate their creativity as a precious gift. This is to well cherish and nurtured too.  

Teach them that there are no limits to what they can achieve when they dare to dream and dare to create. 

Cultivating Emotional Intelligence Nurturing Hearts as Well as Minds

In the pursuit of success, it is easy to overlook the importance of emotional intelligence. The ability to understand and manage one’s own emotions. This goes well while empathizing with others. Yet, it is about the essential trait that shall form the bedrock of meaningful relationships, resilience, and well-being. 

Teach the child all those values of kindness, empathy, and compassion, and model some of the qualities in their own interactions with others.  

Encourage great open communication, active listening, and the expression of emotions in healthy and constructive ways. This shall empower them to navigate the complexities of human relationships with grace and empathy.

Empowering Our Children to Soar

As parents, we are also entrusted with the sacred task of nurturing the seeds of greatness within our children and giving them the wings to soar.  

It is about the journey of love, sacrifice, and unwavering dedication—a journey that holds the promise of a future brimming with infinite possibilities. 

On further cultivating a growth mindset, fostering a love of learning, embracing creativity, and nurturing emotional intelligence.  

This goes well while empowering children to chart their course and seize the boundless opportunities that lie ahead.  

Together, let us give wings to their dreams, and watch with pride as they take flight towards a future filled with hope, purpose, and limitless potential. 

Unraveling The Differences In Competitive Behavior Among Kids

Unraveling The Differences In Competitive Behavior Among Kids

Introduction

In the colorful tapestry of childhood, the thread of competition weaves its way through playgrounds, classrooms, and sports fields. 

Yet, beneath the surface, the child gets a unique hue to the canvas of competitive behavior. 

In this exploration, let’s delve into the diverse manifestations of competitiveness among children, seeking to understand and celebrate the rich spectrum of their experiences. 

The Nature of Competition A Multifaceted Lens

Competition, in its essence, is a natural aspect of human interaction, while driving growth, innovation, and self-discovery.  

For children, sports genetic testing kit serve as a dynamic arena for exploration, learning, and social development.  

However, the expression of competitive behavior might vary widely, while being influenced by a myriad of factors. Some of them include personality, upbringing, and cultural context. 

The Spectrum of Competitive Behavior

  • Intrinsic Motivation: Some of the children are driven by an intrinsic desire to excel. It is well fueled by a passion for mastery and self-improvement.  

Some of the competitive spirit shall arise from within, propelling them to set high standards and persist in the face of challenges. 

  • Extrinsic Incentives: Others might be quite well motivated by external rewards like recognition, praise, or tangible prizes.  

For such children, competition shall serve as a pathway to validation and affirmation, driving them to seek proper approval and validation from others. 

  • Collaborative Competition: In some contexts, competition shall take on a collaborative dimension, fostering teamwork, camaraderie, and mutual support.  

Such children shall thrive in environments where competition is not a zero-sum game but rather it shall share a journey toward collective success. 

  • Social Comparison: For some of the children, competition is intricately linked to social comparison, as it shall measure great worth right against their peers.  

This form of competition can be both motivating and fraught with proper insecurity. This goes well while shaping their sense of self-esteem and identity. 

Nurturing Healthy Competition A Balancing Act

While competition can be a powerful catalyst for growth and achievement. It is well needed to cultivate an environment that fosters healthy attitudes and behaviors.  

Below are some of the strategies for nurturing positive competitive experiences among children: 

  • Emphasize Effort Over Outcome: Encourage children to focus on some of their progress and effort rather than fixating solely on winning or losing.  

Celebrate their perseverance, resilience, and growth mindset. 

  • Promote Sportsmanship and Fair Play: Instill values of integrity, respect, and sportsmanship, emphasizing the importance of playing by the rules. It further shows empathy towards opponents and gracefully accepts both victory and defeat. 
  • Foster a Growth Mindset: Cultivate a culture that values learning and improvement. This goes as the mistakes are seen as opportunities for growth rather than failures.  

Encourage children to embrace challenges, seek proper feedback, and persist in the face of setbacks. 

  • Provide Diverse Opportunities: Offer a variety of competitive and non-competitive activities. This shall further cater to different interests, abilities, and preferences. 

This allows children to explore their passions and discover strengths in a supportive and inclusive environment. 

Embracing Genetic Diversity Celebrating Each Child's Unique Genetic Makeup

As we unravel the genetic tapestry of competitive behavior among children. It further becomes evident that there is no one-size-fits-all approach.  

Each of the children shall inherit a unique blend of genetic predispositions which shall influence the attitudes, motivations, and behaviors towards competition. 

On further embracing genetic diversity and leveraging the understanding of genetic factors, one can further create nurturing environments that support the healthy development of competitive behavior among children.  

Ultimately, it is through embracing and celebrating the richness of each child’s genetic makeup that shall be cultivating a culture of empathy. It also includes inclusivity and resilience in the competitive landscape of childhood. 

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